RT - Journal TY - JOUR A1 - Wendlová, Jaroslava T1 - Scientific medicine in integrative treatment of erectile dysfunction YR - 2015/1/1 JF - Journal of Integrative Nephrology and Andrology JO - J Integr Nephrol Androl SP - 5 OP - 18 VO - 2 IS - 1 UL - http://www.journal-ina.com/article.asp?issn=2394-2916;year=2015;volume=2;issue=1;spage=5;epage=18;aulast=Wendlov;t=5 DO - 10.4103/2225-1243.149992 N2 - Due to the increase in erectile dysfunction (ED) and infertility in world population, there is growing interest in the integrative treatment of these diseases. Therefore, it is raising a market with non-prescription natural supplements. Especially in menu of internet, online shops come increasingly to light new natural over the counter products. Recent sale and use of medicinal plants and their extracts in the treatment of ED are according to the declaration of the producers first of all on a number of the thousand-year-old traditions in some nations, based on the efficacy and safety of these plants, verified in the long-time healing practice. The aim of this article was to make an extensive review of the scientific and professional medical literature and to find out which medicinal plants, minerals and other active substances, sold in the natural products for ED, were evaluated in relevant clinical trials as statistically significant in their efficacy and safety. The review of the literature shows that some marketed medicinal plants and active substances lack clinical studies, the results of some clinical studies related to the same medicinal plant are controversial and some bring significantly positive effects, but their number is minimal (maximum two to five clinical studies). The future is therefore open to starting the number of new clinical trials testing the medicinal plants for the treatment of ED with possible inclusion of some of these plants in evidence-based medicine, if confirming their efficacy and safety. ER -