ORIGINAL ARTICLE |
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Year : 2019 | Volume
: 6
| Issue : 1 | Page : 1-5 |
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25(OH) vitamin D: Serum levels and related factors in hemodialysis patients
Deisy da Silva Fernandes Nascimento, Mariana Caetano da Luz, Karina Valerim Teixeira Remor, Thiago Mamôru Sakae, Marcos de Oliveira Machado
Cursos de Farmácia e Medicina, University of Southern Santa Catarina, Tubarão, SC, Brazil
Correspondence Address:
Prof. Thiago Mamôru Sakae University of Southern Santa Catarina, Tubarao, SC Brazil
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/jina.jina_9_18
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Background and Objective: Advanced chronic renal failure leads to changes in calcium metabolism that cause disturbances in the parathyroid, vascular system, and bones. The 25(OH) Vitamin D plays a key role in regulating calcium metabolism and preventing these complications. The objective of this study was to determine 25(OH) Vitamin D levels in dialysis patients and to relate to clinical and sociodemographic characteristics. Methods: This was a cross-sectional study. The data collection was given by interview and consultation in electronic records, and the dosage of 25(OH) Vitamin D was performed on heparinized plasma samples collected at the beginning of the dialysis session. Results: Of the 77 patients studied, noted that seven (9.1%) showed poor values of 25(OH) Vitamin D and 19 (24.7%) showed insufficient values. As for the presence of comorbidities, 31 (40.3%) reported having diabetes mellitus, and 54 (70.1%) reported having arterial hypertension. It was also observed that the serum levels of 25(OH) Vitamin D are inferior in the carriers of diabetes mellitus and decrease with the increase of age and with the elevation of serum creatinine. The use of Vitamin D supplements presented positive correlation with serum calcium levels. Conclusion: The insufficiency of 25(OH) Vitamin D is frequent in dialysis patients especially in the carriers of diabetes mellitus.
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