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Year : 2018  |  Volume : 5  |  Issue : 2  |  Page : 80-84

Aggressive angiomyxoma of scrotum in a man: A case report and literature review of 73 cases of aggressive angiomyxoma in men

1 Department of Urology, National University Hospital, National University Health System, Singapore
2 Department of Pathology, National University Hospital, National University Health System, Singapore

Correspondence Address:
Dr. Yu Xi Terence Law
Department of Urology, National University Hospital, 1E Kent Ridge Road, NUHS Tower Block, Level 8, 119228
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jina.jina_31_17

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Aggressive angiomyxoma is a mesenchymal tumor arising from the pelvis and perineum, classically seen in women and rarely found in men. Due to its rarity, there is a low index of suspicion for diagnosis. We describe an unusual case of aggressive angiomyxoma in a male with intellectual disability. A thorough review of existing 73 cases was also conducted. This report affirms vimentin as the most sensitive marker and S-100 is the most specific marker. Desmin seems to stain positively and negatively in a sporadic fashion, making it less reliable as an immunohistochemical marker. Wide excision is commonly regarded as the treatment for aggressive angiomyxoma in men. To date, there are no established clinical guidelines on the optimal duration of follow-up. Long-term follow-up may be required even up to 10 years to detect local recurrences.

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