AU - Zhao, Jie AU - Wang, Li AU - Cao, Aili AU - Jiang, Minqian AU - Chen, Xia AU - Peng, Wen TI - Renal Tubulointerstitial Fibrosis: A Review in Animal Models PT - REVI DP - 2015 Jul 1 TA - Journal of Integrative Nephrology and Andrology PG - 75-80 VI - 2 IP - 3 4099- http://www.journal-ina.com/article.asp?issn=2394-2916;year=2015;volume=2;issue=3;spage=75;epage=80;aulast=Zhao;type=0 4100- http://www.journal-ina.com/article.asp?issn=2394-2916;year=2015;volume=2;issue=3;spage=75;epage=80;aulast=Zhao AB - Deterioration of renal function is closely related to renal interstitial fibrosis (RIF). With animal models, we can simulate the pathological changes and progression of disease. Various animal models of RIF are pivotal for clinical treatment and investigation of new drugs. Reviewed here are methods of establishment and mechanism of commonly used animal models of RIF to help researchers select the optimal animal model for different research purposes.