%A Zhao, Jie %A Wang, Li %A Cao, Aili %A Jiang, Minqian %A Chen, Xia %A Peng, Wen %T Renal Tubulointerstitial Fibrosis: A Review in Animal Models %9 Review Article %D 2015 %J Journal of Integrative Nephrology and Andrology %R 10.4103/2225-1243.161428 %P 75-80 %V 2 %N 3 %U http://www.journal-ina.com/article.asp?issn=2394-2916;year=2015;volume=2;issue=3;spage=75;epage=80;aulast=Zhao %8 July 1, 2015 %X Deterioration of renal function is closely related to renal interstitial fibrosis (RIF). With animal models, we can simulate the pathological changes and progression of disease. Various animal models of RIF are pivotal for clinical treatment and investigation of new drugs. Reviewed here are methods of establishment and mechanism of commonly used animal models of RIF to help researchers select the optimal animal model for different research purposes. %0 Journal Article %I Wolters Kluwer Medknow Publications %@ 2394-2916