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CASE REPORT
Year : 2018  |  Volume : 5  |  Issue : 4  |  Page : 140-142

Paroxysmal nocturnal hemoglobinuria manifesting as hemolytic anemia with acute kidney injury


1 Department of Medicine, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India
2 Department of Nephrology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India
3 Department of Medicine, Northern Railway Central Hospital, New Delhi, India

Correspondence Address:
Dr. Manish Ramesh Balwani
Department of Nephrology, Jawaharlal Nehru Medical College, Sawangi, Wardha - 440 003, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jina.jina_12_18

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Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by low-grade, chronic hemolytic anemia accompanied by either thrombocytopenia or leukopenia with usually benign kidney involvement secondary to chronic tubular deposition of hemosiderin. Acute kidney injury (AKI) may be seen during hemolytic crisis. We report the case of a 45-year-old man with PNH who developed reversible AKI requiring temporary hemodialysis support following herpes zoster infection.


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